Sunday, December 6, 2015

Bacteria and their strong cell walls.

Prokaryotes, the bacteria, are the simplest organisms. Prokaryotic cells are small, consisting of cytoplasm surrounded by a plasma membrane and encased within a rigid cell wall, with no distinct interior compartments (figure below). A prokaryotic cell is like a oneroom cabin in which eating, sleeping,
and watching TV all occur in the same room. Bacteria are very important in
the economy of living organisms. They harvest light in photosynthesis, break
down dead organisms and recycle their components, cause disease, and are involved
in many important industrial processes.

Structure of a bacterial cell. Generalized cell organization of a bacterium. Some bacteria have hairlike growths on the outside of the cell called pili.

Strong Cell Walls
Most bacteria are encased by a strong cell wall composed of peptidoglycan, which consists of a carbohydrate matrix (polymers of sugars) that is cross-linked by short polypeptide units. No eukaryotes possess cell walls with this type of chemical composition. With a few exceptions
like TB and leprosy-causing bacteria, all bacteria may beclassified into two types based on differences in their cell walls detected by the Gram staining procedure. The name refers to the Danish microbiologist Hans Christian Gram, who developed the procedure to detect the presence of certain disease-causing bacteria. Gram-positive bacteria have a thick, single-layered cell wall that retains a violet dye from the Gram stain procedure, causing the stained cells to appear purple under a microscope. More complex cell walls have evolved in other groups of bacteria.In them, the wall is multilayered and does not retain the purple dye after Gram staining; such bacteria exhibit the background red dye and are characterized as gramnegative.


The susceptibility of bacteria to antibiotics often depends on the structure of their cell walls. Penicillin and vancomycin, for example, interfere with the ability of bacteria to cross-link the peptide units that hold the carbohydrate chains of the wall together. Like removing all the nails from a wooden house, this destroys the integrity of the matrix, which can no longer prevent water from rushing in,swelling the cell to bursting.Cell walls protect the cell, maintain its shape, and prevent excessive uptake of water. Plants, fungi, and most protists also have cell walls of a different chemical structure, which we will discuss in later chapters.

Long chains of sugars called polysaccharides cover the cell walls of many bacteria. They enable a bacterium to adhere to teeth, skin, food—practically any surface that will support their growth. Many disease-causing bacteria secrete a jellylike protective capsule of polysaccharide around the cell.


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